The incident, which happened during the day, sent thick smoke into the sky and forced residents and nearby traders to run for safety as emergency responders rushed to the scene.
Witnesses said the explosion was sudden and powerful, shaking nearby buildings and causing fear among residents who initially did not understand what had happened.
Many people living close to the depot reported hearing a loud bang followed by flames rising from the premises where gas cylinders are usually stored and distributed.
According to residents, the fire spread rapidly because gas cylinders are highly flammable.
Several traders who operate small businesses near the depot quickly closed their shops and moved their goods away to prevent losses.
Some families were also forced to leave their homes temporarily as the fire threatened nearby houses and structures.
Firefighters from the Nairobi County Fire Department arrived at the scene shortly after the explosion was reported.
They immediately began working to contain the fire and prevent it from spreading further to nearby residential buildings and businesses.
Emergency responders were seen using water hoses and specialized equipment to control the flames while security officers helped manage crowds and keep people away from the dangerous area.
Authorities stated that firefighters worked for several hours to bring the situation under control.
Their quick response helped reduce the risk of further explosions, which could have caused more damage and injuries.
Rescue teams also conducted safety checks around the affected area to ensure that there were no trapped individuals or additional fire risks.
Residents praised the firefighters for their fast action, saying their response prevented the situation from becoming worse.
Some locals described how the fire could be seen from a distance, attracting crowds of people who gathered near the scene before police asked them to move away for safety reasons.
By the time the fire was largely contained, property within and around the depot had been damaged.
Several gas cylinders were destroyed during the explosion, while nearby structures suffered damage caused by the intense heat and flames.
The full extent of property loss is still being assessed by authorities.
Officials have launched investigations to determine what caused the explosion.
Preliminary reports suggest that the blast may have resulted from gas leakage or mishandling of cylinders, although investigators are yet to confirm the exact cause.
Authorities have promised to release more information once the investigation is completed.
Safety experts have continued to warn business owners dealing with gas products to follow strict handling and storage regulations to prevent such incidents.
They stress that gas cylinders must be stored in safe conditions and handled by trained personnel to reduce the risk of accidents.